Research on how engineered materials interact with cells and biological systems, including biodegradable nanosheets, stimuli-responsive hydrogels for drug delivery, and the mechanisms by which material properties influence cell behavior.
A gold nanoparticle's surface charge, more than its size, governs whether it aggregates inside a hydrogel: negatively charged particles aggregate while positively charged ones stay dispersed.
A Design-of-Experiments study of 3D-printed PNIPAm-PEGDA hydrogels links monomer ratio to a 50-fold range in mechanical strength and a predictive model for tuning stiffness, swelling, and drug release.
Zn-loaded PLLA nanosheets release therapeutic zinc ions steadily over 10-12 hours and show antibacterial activity against E. coli, supporting their use as wound-healing patches.
A one-pot, chemical-free laser-ablation route sequentially builds ZnO@graphene-oxide core-shell nanoparticles in water, with longer graphite ablation producing thicker GO shells.
A review traces how cells sense a material's stiffness, morphology, and chemistry, following that signal from the cell surface through nuclear mechanotransduction to changes in gene expression.
